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Control of excisional margins by conventional histopathological techniques in the treatment of skin tumours. An alternative to Mohs' technique
Author(s) -
Breuninger Helmut,
SchaumburgLever Gundula
Publication year - 1988
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711540209
Subject(s) - medicine , skin tumours , dermatology , mohs surgery , pathology
For histological control of excisional margins, routinely fixed tumour specimens or, under certain conditions, specimens fixed immediately in warm formalin are processed in the histology laboratory. Strips are then cut from the undersurface, edge, and cross‐section of the remainder of the specimen and processed further by routine paraffin techniques until H&E‐stained sections of the entire periphery and midsection are available. We suggest that the method is simple, easy to apply, and suitable for the assessment of excisional margins of a variety of skin tumours. Extremely low recurrence rates over a relatively long follow‐up period substantiate the effectiveness of the method.