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Reaction of monoclonal anti Leu M1—a myelomonocytic marker (CD15)—with normal and neoplastic epithelia
Author(s) -
Sewell Herb F.,
Jaffray Bruce,
Thompson W. Douglas
Publication year - 1987
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711510407
Subject(s) - cd15 , pathology , monoclonal antibody , monoclonal , biology , immunology , medicine , antibody , microbiology and biotechnology , stem cell , cd34
The present study describes the distribution of Leu M1 (CD15) immunoreactivity in 13 normal epithelia and 14 epithelial neoplasms. The findings are compared with those obtained using other epithelial markers. Cautionary points and broad recommendations are made with regard to use of anti Leu M1 antibody.