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Immunohistological study in chordomas
Author(s) -
Coindre JeanMichel,
Rivel Janine,
Trojani Monique,
De Mascarel Isabelle,
De Mascarel Antoine
Publication year - 1986
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711500110
Subject(s) - vimentin , cytokeratin , neurofilament , staining , pathology , immunohistochemistry , s100 protein , positive staining , immunocytochemistry , keratin , biology , medicine
An immunohistological study of 15 chordomas, six chondrosarcomas, four liposarcomas and seven carcinomas on paraffin embedded samples using anti‐cytokeratin, anti‐epithelial membrane antigen (EMA), anti‐S100 protein, anti‐vimentin and anti‐neurofilaments showed that chordomas has a characteristic immuno‐staining, i.e. positive for cytokeratin, EMA, S100 protein and vimentin; and negative for neurofilaments. This immuno‐staining allows a clear distinction of chordomas from other tumours.