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Lipid in the human gallbladder mucosa. A histochemical study by light and electron microscopy
Author(s) -
English Martin,
Hopwood David
Publication year - 1985
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711460406
Subject(s) - phospholipid , electron microscope , epithelium , connective tissue , gallbladder , cholesterol , lipid droplet , chemistry , apex (geometry) , cholecystitis , pathology , biology , anatomy , biochemistry , medicine , membrane , physics , optics
The distribution of lipids in the epithelium of 70 gallbladders removed for cholecystitis was investigated histochemically. Lipid was demonstrated in 68 gallbladders—cholesterol and its esters, triglycerides, free fatty acids and phospholipids. Neutral lipid was found at the bases of epithelial cells in 90 per cent and at the apex in 10 per cent of the gallbladders. Phospholipid was shown at the apex of epithelial cells in 64 per cent of the gallbladders. Electron microscopy in 12 specimens revealed cholesterol in and between the epithelial cells and in the underlying connective tissue.