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Age related detection of tissue amyloid P in the skin
Author(s) -
Khan A. M.,
Walker F.
Publication year - 1984
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711430305
Subject(s) - amyloid (mycology) , fetus , immunohistochemistry , pathology , biology , medicine , pregnancy , genetics
The presence of tissue amyloid P component in normal skin from fetuses and children was studied using direct, fluorescent, immunohistochemical techniques on frozen sections. Tissue amyloid P is not detected in fetuses or in children up to the age of 2 years but from the age of 4 years upwards it is readily detected and invariably present. Though the function of human amyloid P is unknown its role appears to be age or maturity related.