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Membrane‐bound structures at the interface between tumour and dermis in basal cell carcinoma. An ultrastructural study
Author(s) -
Morley Susan M.,
Rennison A.,
Macadam R. F.
Publication year - 1983
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711400308
Subject(s) - dermis , basal lamina , ultrastructure , basal cell carcinoma , pathology , cytoplasm , stromal cell , anatomy , epidermis (zoology) , basal (medicine) , biology , basal cell , chemistry , medicine , microbiology and biotechnology , endocrinology , insulin
During an ultrastructural study of the interface area between tumour and dermis in 23 basal cell carcinoma (BCC), membrane‐bound structures were noted in the dermis adjacent to the basal lamina in 12 tumours (52 per cent), but none of the controls. Serial sectioning demonstrated cytoplasmic connections between these structures and tumour cells. Their formation and interaction with adjacent stromal cells is discussed.