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As assessment of the surface charge of single resident and exudate macrophages and multinucleate giant cells
Author(s) -
Papadimitriou J. M.
Publication year - 1982
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711380103
Subject(s) - multinucleate , exudate , giant cell , macrophage , ultrastructure , biophysics , biology , chemistry , microbiology and biotechnology , anatomy , botany , in vitro , biochemistry , genetics
Abstract The relative magnitude of the negative charge per unit area on the surface of resident and exudate macrophages as well as multinucleate giant cells was assessed by cytophotometric and ultrastructural techniques. The results indicate that the surface of resident macrophages possesses a higher negative charge per unit area than that of exudate macrophages or multinucleate giant cells. This may partly explain the relative ease of fusion of exudate macrophages into multinucleate giant cells since the electrostatic forces of repulsion are likely to be lower than between resident macrophages.