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Delayed infarction of spinal cord white matter following X‐irradiation
Author(s) -
Blakemore W. F.,
Palmer A. C.
Publication year - 1982
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711370402
Subject(s) - spinal cord , white matter , medicine , grey matter , decompression sickness , infarction , cats , anatomy , thrombosis , necrosis , lumbar spinal cord , cord , pathology , decompression , surgery , radiology , cardiology , magnetic resonance imaging , myocardial infarction , psychiatry
The thoraco‐lumbar spinal cord of 4 cats were subjected to 4000 RADS of X‐irradiation. Between 3 and 5 mth afterwards the animals developed weakness of the hind‐legs and became incoordinated. Small infarcts were found in the white matter of the irradiated area of spinal cord, accompanied by neuronal death and oedema of the grey matter close to the central canal. Ultrastructurally the infarcts were shown to stem from necrosis and thrombosis of small blood vessels. Comparison is made with the pathogenesis of spinal cord infarction that occurs in decompression sickness.