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Influence of aqueous fixation on articular surface morphology. A reflected light interference microscope study
Author(s) -
Wilson N. H. F.,
Gardner D. L.
Publication year - 1980
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711310405
Subject(s) - fixation (population genetics) , glutaraldehyde , interference microscopy , microscopy , morphology (biology) , polarized light microscopy , materials science , biomedical engineering , anatomy , chemistry , optics , pathology , biology , medicine , chromatography , biochemistry , genetics , physics , gene
Fresh, unfixed temporomandibular fibrous articular surfaces from baboons were examined by reflected light interference microscopy. The appearances, recorded photographically, were compared with those of joints subjected to aqueous fixation in buffered glutaraldehyde and formalin. Fixation caused readily detectable, measureable changes in articular surface morphology. Reflected light interference microscopy is a valuable technique for the demonstration of the effects of fixation on articular surface morphology.