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The enzyme histochemistry of metastasising basal cell carcinoma of the skin
Author(s) -
Elias E. A.,
Elias R. A.,
Bijlsma P. J.,
Tazelaar D. J.
Publication year - 1980
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711310305
Subject(s) - basal cell carcinoma , immunohistochemistry , enzyme , basal cell , pathology , basal (medicine) , biology , carcinoma , medicine , biochemistry , endocrinology , insulin
A case of metastasising basal cell carcinoma of the skin is presented. The tumour was analysed by enzyme histochemistry and cytology and criteria are set out for establishing the diagnosis of this rather uncommon entity. The lesion is apparently rich in enzymes of the pentose shunt and tricarboxylic acid cycles and shows insignificant acid phosphatase activity and no activity of alkaline phosphatase. These enzyme histochemical findings are thought to be important in the differential diagnosis of various types of tumour.