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A comparison of the inhibitory effects of disodium pyrophosphate and disodium ethane‐hydroxy‐1, 1‐diphosphonate on simple calcergy
Author(s) -
McClure J.
Publication year - 1979
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711290307
Subject(s) - pyrophosphate , inhibitory postsynaptic potential , chemistry , simple (philosophy) , medicine , biochemistry , philosophy , enzyme , epistemology
Both disodium pyrophosphate and disodium ethane-hydroxy-1, 1-diphosphate inhibit the reaction of simple calcergy induced in the mouse by lead acetate. The pyrophosphate is effective only by a direct interaction with the lead salt and the disphosphonate is effective only before the occurrence of histochemically demonstrable calcification.