Premium
A cell line from an induced carcinoma of mouse rectum
Author(s) -
Franks L. M.,
Hemmings Valerie J.
Publication year - 1978
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711240108
Subject(s) - cell culture , in vitro , electron microscope , microbiology and biotechnology , rectum , carcinoma , cell , morphology (biology) , pathology , biology , chemistry , anatomy , medicine , biochemistry , genetics , physics , optics
A tissue culture cell line has been established from one out of seven induced carcinomas of mouse large intestine. The cells have an epithelial morphology and form tumour acini in vitro. Electron microscopy shows that the cells have retained some differentiated characters, including junctional complexes and microvilli with attached glycoprotein strands both in the acini and at the free margins of the cell sheets.