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“Epithelial” foci of presumptive neural origin in cultures of normal mouse colon
Author(s) -
Franks L. M.,
Hamilton Elizabeth,
Hemmings Valerie J.
Publication year - 1978
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711240105
Subject(s) - ultrastructure , epithelium , biology , pathology , cell bodies , schwann cell , cell culture , microbiology and biotechnology , cell , nerve cells , anatomy , neuroscience , medicine , central nervous system , genetics
Patches of cells, which at the light-microscope level appear to be epithelial, persist for several months in cultures of normal mouse colon. Ultrastructural studies showed that these cells were nerve-associated and were probably derived from the Schwann cell-satellite cell group. True epithelial cells all died out within the first 2 wk of culture, and epithelial cell lines could not be established.