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Comparative ultrastructural morphology of aurosomes produced by colloidal gold and soluble gold salts
Author(s) -
Ghadially F. N.,
Thomas I.,
Lalonde JM. A.
Publication year - 1977
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711230308
Subject(s) - ultrastructure , colloidal gold , electron microscope , morphology (biology) , granule (geology) , chemistry , colloid , colloidal particle , biophysics , particle (ecology) , chemical engineering , nanotechnology , materials science , anatomy , nanoparticle , organic chemistry , biology , composite material , physics , ecology , genetics , engineering , optics
Intra-articular administration of colloidal gold produced aurosomes which contained spherical electron-dense granules and also often some very fine electron-dense particles. Intra-articular administration of aurothioglucose produced aurosomes of a morphology similar to that reported to occur after administration of sodium aurothiomalate. These aurosomes produced by soluble gold salts are characterised by particle and granule-studded membranous formations which present in profile as rod-like and curled filamentous structures. On the basis of morphological differences two types of aurosomes should be recognised, the "Type I or granular aurosome" and the "Type II or membranous aurosome".