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Mannosidosis—pathogenesis of lesions in exocrine cells
Author(s) -
Jolly R. D.,
Thompson K. G.
Publication year - 1977
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711210109
Subject(s) - citation , library science , path (computing) , computer science , programming language
The finding of zymogen granules within lysosomal storage vesicles in pancreatic exocrine tissue in bovine mannosidosis may explain the widespread vacuolation of exocrine cells in this disease. It is uncertain if they enter the lysosomal system by the process of crinophagy but if so it would indicate that this regulatory mechanism could operate in normal exocrine tissue as well.