Premium
An experimental kidney disease in dogs produced by injection of heterologous antisera to dog tubular fraction 3 antigen
Author(s) -
Barabas Arpad Z.,
Lannigan Robert
Publication year - 1976
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711200103
Subject(s) - heterologous , antiserum , antigen , immune system , antibody , glomerulonephritis , kidney , medicine , immunology , pathology , biology , genetics , gene
Glomerular disease characterised by morphological alterations of the glomerular basement membrane and the mesangium was produced in dogs by injections of heterologous anti-dog renal tubular fraction 3 antibody. The renal lesion was characterised by irregular thickening of the glomerular basement membrane, with electron-dense deposits and loose granular material within it.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom