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Experimental allergic sialgadenitis VIII. Acute parotitis following intraductal instillation of antiserum to salivary antigens in the rat
Author(s) -
Sela J.,
Bab J. A.,
Rosenmann E.,
Boss J. H.
Publication year - 1976
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711190302
Subject(s) - hebrew , medical school , medicine , boss , pediatrics , family medicine , classics , history , medical education , materials science , metallurgy
Antiserum to ammonium sulphate-soluble proteins of rat saliva was raised in rabbits. The introduction of this antiserum, via the excretory duct, into the parotid gland of rats induced severe acute sialoadentis. It is suggested that the inflammatory response developed as a result of formation of immune complexes, composed of acinar epithelial antigens and the antibodies introduced from without.