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Histological effects of ductal ligation of salivary glands of the cat
Author(s) -
Harrison J. D.,
Garrett J. R.
Publication year - 1976
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711180407
Subject(s) - ligation , salivary gland , salivary gland diseases , pathology , medicine , biology , anatomy
Forty-two submandibular, 32 sublingual and 31 parotid glands have been examined microscopically after ductal ligation avoiding the nerves for periods from 1 day to 1 yr. After an initial increase in size, there was over-all atrophy in all three glands. In the parotid gland the response was uniform and there was progressive atrophy until most of the acini were extremely atrophic. However, in the submandibular and sublingual glands the response was very variable, and although in some glands most of the acini were extremely atrophic, in other glands there was far less atrophy and most of the remaining acini appeared more or less similar to normal despite prolonged ligation. These results contrast with those of earlier experimental studies on ductal ligation, but have similarities with observations on the behaviour of human salivary glands.