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The surface morphology of the phagocytosis of micro‐organisms by peritoneal macrophages
Author(s) -
Walters M. NI.,
Papadimitriou J. M.,
Robertson T. A.
Publication year - 1976
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711180404
Subject(s) - filopodia , phagocytosis , bacillus cereus , microbiology and biotechnology , lamellipodium , scanning electron microscope , biology , staphylococcus aureus , cryptococcus neoformans , chemistry , cell , bacteria , materials science , cytoskeleton , actin , biochemistry , genetics , composite material
Scanning electron-microscopic studies of phagocytosis of various micro organisms by murine peritoneal macrophages has been made. Bacillus cereus, Staphylococcus aureus, and Brewer's yeast were easily ingested, whereas Cryptococcus neoformans was not. The development of intricate and tenuous filopodia preceded close-surface attachment, after which both thin and thicker lamellipodia invested the micro-organisms. Loss of the normal surface ridges characterised the replete cell. The technique of scanning electron microscopy is easily reproducible and adds a new parameter to the morphological appreciation of a fundamental biological phenomenon.