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Alkaline phosphatase in craniopharyngiomas
Author(s) -
Timperley W. R.,
Turner P.,
Davies S.
Publication year - 1971
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711030408
Subject(s) - epithelium , alkaline phosphatase , ameloblastoma , basal (medicine) , pathology , biology , dentigerous cyst , cyst , anatomy , medicine , enzyme , maxilla , endocrinology , biochemistry , insulin
THE derivation of the epithelium from which craniopharyngiomas arise is in doubt. Willis (1953) and Russell and Rubinstein (1959) state that these tumours are not distinguishable from “epitheliomas” in which squamous and basal cells are both present. Timperley (1968 a ), in a histochemical investigation, showed that craniopharyngiomas differed from squamous epithelium and epidermal cyst epithelium in that they contained a high activity of alkaline phosphatase and in this respect they closely resembled the ameloblastoma of the jaw and the developing tooth bud. The present paper is a histochemical and chemical analysis comparing several more craniopharyngiomas with dental and dentigerous cysts.