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Not just angiogenesis—wider roles for the angiopoietins
Author(s) -
Jones Pamela F
Publication year - 2003
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1452
Subject(s) - angiogenesis , angiopoietin receptor , angiopoietin , biology , cancer research , vegf receptors , vascular endothelial growth factor
Abstract Since the discovery of the angiopoietins, much interest has been focused on their biological actions and their potential use as therapeutic targets. It is generally accepted that the angiopoietins play an important role in angiogenesis and hence are described as angiogenic factors. However, it is becoming increasingly clear that this is not their only role and it is likely that the angiopoietins have important roles in a wider range of biological and pathological functions. Copyright © 2003 John Wiley & Sons, Ltd.