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Synthesis of hydrolytically and oxidation‐responsive networks using thiol‐ene “click” chemistry with pentaerythritol tetrakis(3‐mercaptopropionate) and tri/tetra‐acrylates
Author(s) -
Kazybayeva Diara S.,
Irmukhametova Galiya S.,
Khutoryanskiy Vitaliy V.
Publication year - 2021
Publication title -
polymers for advanced technologies
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.61
H-Index - 90
eISSN - 1099-1581
pISSN - 1042-7147
DOI - 10.1002/pat.5147
Subject(s) - pentaerythritol , hydrogen peroxide , trimethylolpropane , materials science , thermogravimetric analysis , degradation (telecommunications) , hydrolysis , polymer chemistry , fourier transform infrared spectroscopy , tetra , chemistry , organic chemistry , chemical engineering , polyurethane , telecommunications , fire retardant , medicinal chemistry , computer science , engineering
Thiol‐ene click reactions of pentaerythritol tetrakis(3‐mercaptopropionate) with pentaerythritol tetraacrylate and trimethylolpropane triacrylate were used to prepare polymeric degradable networks. The structure and properties of these networks were studied using Fourier‐transform infrared and Raman spectroscopy, thermal gravimetric analysis and scanning electron microscopy. Degradation of these materials was evaluated in different media including phosphate buffer with and without esterase as well as in oxidative environment with hydrogen peroxide. Exposure of the samples to these media results in their degradation. Slow hydrolytic degradation was observed in phosphate buffer and it was not accelerated by the presence of an enzyme. Faster degradation is observed in solutions of hydrogen peroxide. The mechanisms of this degradation are discussed.