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Construction of albumin multilayer coating onto plasma treated poly(vinyl chloride) via electrostatic self‐assembly
Author(s) -
Ji Jian,
Tan Qinggang,
Shen Jiacong
Publication year - 2004
Publication title -
polymers for advanced technologies
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.61
H-Index - 90
eISSN - 1099-1581
pISSN - 1042-7147
DOI - 10.1002/pat.475
Subject(s) - polyethylenimine , materials science , albumin , adhesion , vinyl chloride , coating , contact angle , chemical engineering , chloride , layer (electronics) , polymer chemistry , surface modification , nuclear chemistry , chromatography , chemistry , composite material , copolymer , polymer , biochemistry , transfection , metallurgy , engineering , gene
Multilayer films consisting of polyethylenimine (PEI) and albumin were successffully prepared on plasma treated poly(vinyl chloride) (PVC) via electrostatic self‐assembly of the PEI and albumin. The layer‐by‐layer assembly of the PEI/albumin on plasma treated PVC was monitored by contact angle and 125 I radiolabeled method. The stability of the mutilayer coating was determined by 125 I radiolabeled method. The results revealed that less than 10% albumin was eluted by a phosphate buffered saline (PBS) solution in 45 days. The static platelet adhesion indicated that the PEI/albumin deposited PVC could resist the platelet adhesion effectively. Such an easy processing and shape‐independent method may have good potential for surface modification of cardiovascular device. Copyright © 2004 John Wiley & Sons, Ltd.