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Amphiphilic copolymers with poly(meth)acrylic acid chains “grafted from” caprolactone 2‐(methacryloyloxy)ethyl ester‐based backbone
Author(s) -
Neugebauer Dorota,
Bury Katarzyna,
Paprotna Magdalena,
Biela Tadeusz
Publication year - 2013
Publication title -
polymers for advanced technologies
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.61
H-Index - 90
eISSN - 1099-1581
pISSN - 1042-7147
DOI - 10.1002/pat.3195
Subject(s) - copolymer , polymer chemistry , acrylate , amphiphile , acrylic acid , side chain , ethyl acrylate , polymerization , caprolactone , materials science , radical polymerization , polymer , composite material
Well‐defined amphiphilic graft copolymers containing hydrophilic poly((meth)acrylic acid) (PMAA) or poly(acrylic acid) (PAA) side chains with gradient and statistical distributions were synthesized. For this purpose, the hydroxy‐functionalized copolymers with various gradient degrees, in which 2‐(6‐hydroxyhexanoyloxy)ethyl (meth)acrylate units (caprolactone 2‐[methacryloyloxy]ethyl ester, CLMA) formed strong gradient with tert ‐butyl acrylate (tBA), slight gradient copolymers with tert ‐butyl (meth)acrylate (tBMA), and statistical copolymers with methyl (meth)acrylate (MMA) were modified to bromoester multifunctional macroinitiators, P(tBMA‐ grad ‐BrCLMA), P(BrCLMA‐ grad ‐tBA), and P(BrCLMA‐ co ‐MMA). In the next step, they were applied in controlled radical polymerization of t BMA and tBA yielding graft copolymers with various lengths of side chains as well as graft densities. Further, the tert ‐butyl groups in copolymers were successfully removed via acidolysis in the presence of trifluoracetic acid, which caused transformation of the hydrophobic graft copolymers into amphiphilic ones with ability of self‐assembly for the future biomedical applications. Copyright © 2013 John Wiley & Sons, Ltd.