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Prepation of poly( N ‐isopropylacrylamide)‐grafted silica gel and its temperature‐dependent interaction with proteins
Author(s) -
Yoshioka Hiroshi,
Mikami Masato,
Nakai Tomoko,
Mori Yuichi
Publication year - 1995
Publication title -
polymers for advanced technologies
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.61
H-Index - 90
eISSN - 1099-1581
pISSN - 1042-7147
DOI - 10.1002/pat.1995.220060606
Subject(s) - poly(n isopropylacrylamide) , materials science , chemical engineering , polymer chemistry , polymer science , composite material , polymer , copolymer , engineering
Poly( N ‐isopropylacrylamide) oligomer was immobilized onto a silica gel surface. The gel adsorbed a hydrophobic protein γ‐globulin (IgG) at 37°C, however, did not adsorb IgG at 24°C. The adsorbed IgG at 37°C was adsorbed by lowering the temperatue, No adsorption of a hydrophilic protein bovin serum albumin (BSA) onto this matrix was observed at 37°C nor 24°C.