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Adsorption of bovine serum albumin to acrylamide–itaconic acid hydrogels
Author(s) -
Karadaǧ Erdener,
Saraydin Dursun,
Öztop H. Nursevin,
Güven Olgun
Publication year - 1994
Publication title -
polymers for advanced technologies
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.61
H-Index - 90
eISSN - 1099-1581
pISSN - 1042-7147
DOI - 10.1002/pat.1994.220051006
Subject(s) - itaconic acid , self healing hydrogels , acrylamide , adsorption , bovine serum albumin , swelling , nuclear chemistry , diffusion , materials science , polymer chemistry , chemistry , chromatography , polymer , organic chemistry , copolymer , composite material , physics , thermodynamics
In this study, acrylamide–itaconic acid hydrogels containing different amounts of itaconic acid prepared by irradiating with γ radiation are discussed. They have been used in experiments of swelling, diffusion and bovine serum albumin (BSA) adsorption. Maximum and minimum swellings were observed with water (1520%) and BSA (890%), respectively. Diffusion of water, NaCl and BSA within hydrogels were found to be non‐Fickian in character. In the experiments of BSA adsorption, type III adsorption was found. The hydrogel prepared with 60 mg itaconic acid and irradiated at 2.00 kGy was found to be the best adsorption system for BSA. The adsorption capacity of acrylamide–itaconic acid hydrogel was found to exceed that of acrylamide hydrogel by more than 80–100%.