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The responses of preosteoblasts to collagen/hyaluronic acid polyelectrolyte multilayer coating on titanium
Author(s) -
Li Xiaojun,
Luo Qiaojie,
Huang Ying,
Li Xiaodong,
Zhang Feng,
Zhao Shifang
Publication year - 2012
Publication title -
polymers for advanced technologies
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.61
H-Index - 90
eISSN - 1099-1581
pISSN - 1042-7147
DOI - 10.1002/pat.1953
Subject(s) - quartz crystal microbalance , materials science , coating , polyelectrolyte , hyaluronic acid , scanning electron microscope , layer (electronics) , chemical engineering , titanium , layer by layer , polymer , composite material , chemistry , organic chemistry , adsorption , engineering , metallurgy , biology , genetics
The purpose of this study was to investigate the effect of Collagen/hyaluronic acid (Col/HA) polyelectrolyte multilayer (PEM) coating on the behaviors and function of pre‐osteoblastic cells. Col/HA PEM coating was fabricated on acid etched Ti disc via layer‐by‐layer technique. The formation and properties of Col/HA PEM coating were investigated using scanning electron microscope (SEM), contact angle and quartz crystal microbalance (QCM). Moreover, mouse preosteoblasts were used to evaluate the effect of Col/HA PEM coating on cell behaviors and function. The results of in vitro evaluations showed that the Col/HA PEM coating could accelerate the proliferation and differentiation of preosteoblasts cells. Copyright © 2011 John Wiley & Sons, Ltd.