The responses of preosteoblasts to collagen/hyaluronic acid polyelectrolyte multilayer coating on titanium | Zendy

Li Xiaojun | Zendy; Luo Qiaojie | Zendy; Huang Ying | Zendy; Li Xiaodong | Zendy; Zhang Feng | Zendy; Zhao Shifang | Zendy

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The responses of preosteoblasts to collagen/hyaluronic acid polyelectrolyte multilayer coating on titanium

Author(s) -

Li Xiaojun,

Luo Qiaojie,

Huang Ying,

Li Xiaodong,

Zhang Feng,

Zhao Shifang

Publication year - 2012

Publication title -

polymers for advanced technologies

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.61

H-Index - 90

eISSN - 1099-1581

pISSN - 1042-7147

DOI - 10.1002/pat.1953

Subject(s) - quartz crystal microbalance , materials science , coating , polyelectrolyte , hyaluronic acid , scanning electron microscope , layer (electronics) , chemical engineering , titanium , layer by layer , polymer , composite material , chemistry , organic chemistry , adsorption , engineering , metallurgy , biology , genetics

The purpose of this study was to investigate the effect of Collagen/hyaluronic acid (Col/HA) polyelectrolyte multilayer (PEM) coating on the behaviors and function of pre‐osteoblastic cells. Col/HA PEM coating was fabricated on acid etched Ti disc via layer‐by‐layer technique. The formation and properties of Col/HA PEM coating were investigated using scanning electron microscope (SEM), contact angle and quartz crystal microbalance (QCM). Moreover, mouse preosteoblasts were used to evaluate the effect of Col/HA PEM coating on cell behaviors and function. The results of in vitro evaluations showed that the Col/HA PEM coating could accelerate the proliferation and differentiation of preosteoblasts cells. Copyright © 2011 John Wiley & Sons, Ltd.

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