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β‐cyclodextrin‐based polymeric nano‐receptor: the self‐assembly of cyclodextrin‐appended comb‐copolymer
Author(s) -
Kang Yan,
Yuan Jinying,
Yan Qiang,
Zheng Liyao,
Zhou Lilin
Publication year - 2012
Publication title -
polymers for advanced technologies
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.61
H-Index - 90
eISSN - 1099-1581
pISSN - 1042-7147
DOI - 10.1002/pat.1863
Subject(s) - copolymer , cyclodextrin , micelle , ferrocene , materials science , polymer chemistry , polymerization , cellulose , click chemistry , self assembly , molecule , nano , combinatorial chemistry , chemical engineering , organic chemistry , nanotechnology , chemistry , polymer , electrochemistry , aqueous solution , electrode , composite material , engineering
Well‐defined β‐cyclodextrin (β‐CD)‐appended biocompatible comb‐copolymer ethyl cellulose‐ graft ‐poly (ε‐caprolactone) (EC‐ g ‐PCL) was synthesized via the combination of ring‐opening polymerization (ROP) and click chemistry. The resulting products were characterized by 1 H NMR, FT‐IR spectroscopy, and GPC. The synthesized comb‐copolymer could assemble to micelles, with the surface covered by β‐CD. The inclusion with ferrocene derivation was investigated by cyclic voltammetric (CV) experiments, which indicated the potential application of the micelles as nano‐receptors for molecule recognization and controlled drug release. Copyright © 2011 John Wiley & Sons, Ltd.