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Patterning of cells on a PVC film surface functionalized by ion irradiation
Author(s) -
Jung ChanHee,
Hwang InTae,
Kwon HoJe,
Nho YoungChang,
Choi JaeHak
Publication year - 2010
Publication title -
polymers for advanced technologies
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.61
H-Index - 90
eISSN - 1099-1581
pISSN - 1042-7147
DOI - 10.1002/pat.1437
Subject(s) - irradiation , x ray photoelectron spectroscopy , materials science , contact angle , ion , fourier transform infrared spectroscopy , adhesion , surface modification , vinyl chloride , chemical engineering , polyvinyl chloride , chloride , analytical chemistry (journal) , polymer chemistry , composite material , organic chemistry , polymer , chemistry , copolymer , physics , nuclear physics , engineering , metallurgy
Micropatterns of cells on a poly(vinyl chloride) (PVC) film surface were created by using ion irradiation. A PVC film was irradiated with H + ions through a pattern mask in order to create patterns of the hydrophilic/hydrophobic regions on the PVC surface. The effect of ion irradiation on the surface properties of the PVC film was characterized by using Fourier transform‐infrared spectroscopy (FT‐IR), water contact angle measurement, and X‐ray photoelectron spectroscopy (XPS). The results revealed that the chemical environment of the PVC film surface was effectively changed by ion irradiation due to dehydrochlorination and oxidation. The in vitro cell culture on the patterned PVC film surface showed selective adhesion and proliferation of the cells on the ion‐irradiated regions. Well‐defined 50 µm patterns of the cells were obtained on the PVC film surface irradiated to 1 × 10 15 ions/cm 2 . Copyright © 2009 John Wiley & Sons, Ltd.