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Modeling and Simulation of the Aqueous Humor Flow in the Human Eye
Author(s) -
Dörsam Simon,
Olkhovskiy Vladislav,
Friedmann Elfriede
Publication year - 2019
Publication title -
pamm
Language(s) - English
Resource type - Journals
ISSN - 1617-7061
DOI - 10.1002/pamm.201900462
Subject(s) - human eye , glaucoma , intraocular pressure , aqueous humor , flow (mathematics) , retinal , action (physics) , finite element method , ophthalmology , computer science , medicine , mechanics , physics , artificial intelligence , quantum mechanics , thermodynamics
A mathematical model for the physiology of the aqueous humor flow in the human eye is developed. The governing equations are the Stokes and Darcy equations with certain physical characteristic parameters. We extend the model to describe diseases like glaucoma and retinal diseases and model their treatment. The developed models are solved with the mixed Finite Element method and the flow is visualized in a three‐dimensional eye model. An individual physiology of a healthy eye or of an eye with glaucoma can be represented by adjusting the parameters. We calculate the intraocular pressure and quantify the pressure decrease after a certain treatment. In case of retinal diseases we calculate the drug distribution and quantify the drug amount at the location of action.