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Mechanobiological processes of tissue engineered cartilage replacement materials
Author(s) -
Nachtsheim Julia,
Markert Bernd,
Stoffel Marcus
Publication year - 2017
Publication title -
pamm
Language(s) - English
Resource type - Journals
ISSN - 1617-7061
DOI - 10.1002/pamm.201710075
Subject(s) - articular cartilage , cartilage , materials science , scaffold , viscoelasticity , biomedical engineering , compression (physics) , material properties , composite material , engineering , osteoarthritis , medicine , anatomy , pathology , alternative medicine
A new therapeutic approach in the treatment of small focal articular defects is the implantation of an acellular collagen‐based scaffold. Replacement materials need to fulfil high requirements in terms of biocompatility and mechanical properties. Ideally, they feature similar mechanical properties as native articular cartilage. The aim of this study is to experimentally and numerically analyse a clinically available implant. Therefore, we perform unconfined compression tests and use a phenomenological material model to identify material parameters of the viscoelastic material. (© 2017 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim)