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Simulation of the gelation process of hydrogel droplets in 3D bioprinting
Author(s) -
Zhou Bei,
Heider Yousef,
Blaeser Andreas,
Raith Stefan,
Fischer Horst,
Markert Bernd
Publication year - 2016
Publication title -
pamm
Language(s) - English
Resource type - Journals
ISSN - 1617-7061
DOI - 10.1002/pamm.201610047
Subject(s) - viscoelasticity , materials science , polymer , process (computing) , work (physics) , phenomenological model , phase (matter) , thermal , chemical engineering , mechanics , composite material , thermodynamics , chemistry , computer science , physics , engineering , organic chemistry , quantum mechanics , operating system
The aim of this work is to numerically simulate the gelation of a crosslinking polymer, which is a very complex process involving chemical reactions and phase transitions from a viscous fluid to a viscoelastic solid. A phenomenological model is proposed to simulate the gelation process of agarose droplets, considering the thermal boundary conditions. The numerical model is implemented using the finite element package FlexPDE. The temperature‐ and time‐dependent degree of gelation and the deformation of the droplets during the gelation process are investigated. (© 2016 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim)