Multiscale hierarchical mechanics in soft tissues | Zendy

Marino Michele | Zendy; Vairo Giuseppe | Zendy; Wriggers Peter | Zendy

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Multiscale hierarchical mechanics in soft tissues

Author(s) -

Marino Michele,

Vairo Giuseppe,

Wriggers Peter

Publication year - 2015

Publication title -

pamm

Language(s) - English

Resource type - Journals

ISSN - 1617-7061

DOI - 10.1002/pamm.201510010

Subject(s) - homogenization (climate) , soft tissue , multiscale modeling , cell mechanics , computational mechanics , continuum mechanics , computer science , biological system , mechanics , chemistry , physics , biology , pathology , finite element method , bioinformatics , thermodynamics , medicine , biodiversity , ecology , biochemistry , cytoskeleton , cell

In this paper, the mechanics of soft tissues is modeled by introducing a novel polyconvex strain‐energy function able to include tissue structured hierarchical arrangement and by reducing model complexity via multiscale homogenization techniques. The case of arterial tissue is successfully addressed by obtaining a quantitative prediction of the age‐dependent alterations in aorta mechanics incorporating histological remodeling mechanisms and biochemical variations. (© 2015 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim)

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