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Active strain and activation models in cardiac electromechanics
Author(s) -
Rossi Simone,
RuizBaier Ricardo,
Pavarino Luca F.,
Quarteroni Alfio
Publication year - 2011
Publication title -
pamm
Language(s) - English
Resource type - Journals
ISSN - 1617-7061
DOI - 10.1002/pamm.201110051
Subject(s) - electromechanics , cardiac muscle , contraction (grammar) , ionic bonding , membrane potential , gating , biophysics , electrophysiology , artificial muscle , transmembrane protein , chemistry , computer science , physics , anatomy , actuator , neuroscience , medicine , artificial intelligence , biology , ion , biochemistry , receptor , organic chemistry , quantum mechanics
We present a model for mechanical activation of the cardiac tissue depending on the evolution of the transmembrane electrical potential and certain gating/ionic variables that are available in most of electrophysiological descriptions of the cardiac membrane. The basic idea consists in adding to the chosen ionic model one ordinary differential equation for the kinetics of the mechanical activation function. A relevant example illustrates the desired properties of the proposed model, such as delayed muscle contraction and correct magnitude of the muscle fibers' shortening. (© 2011 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim)