An Analysis of Drug Dissolution Rates in the USP 24 Type 2 Apparatus | Zendy

McDonnell David | Zendy; Redmond Brendan | Zendy; D'Arcy Deirdre M | Zendy; Healy Anne Marie | Zendy; Corrigan Owen I | Zendy

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An Analysis of Drug Dissolution Rates in the USP 24 Type 2 Apparatus

Author(s) -

McDonnell David,

Redmond Brendan,

D'Arcy Deirdre M,

Healy Anne Marie,

Corrigan Owen I

Publication year - 2009

Publication title -

pamm

Language(s) - English

Resource type - Journals

ISSN - 1617-7061

DOI - 10.1002/pamm.200910314

Subject(s) - dissolution , mass transfer , boundary layer , type (biology) , boundary (topology) , dissolution testing , drug , chemistry , chemical engineering , materials science , analytical chemistry (journal) , chromatography , thermodynamics , physics , engineering , mathematics , pharmacology , mathematical analysis , geology , medicine , paleontology , biopharmaceutics classification system

This paper applies boundary layer theory to the process of drug dissolution in the USP 24, Type 2 Apparatus. The mass transfer rate from the top flat surface of a compact in various positions within the device is evaluated by means of a Pohlhausen integral method. (© 2009 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim)

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