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Feedback protocol laws for immunotherapy
Author(s) -
Kassara K.,
Moustafid A.
Publication year - 2007
Publication title -
pamm
Language(s) - English
Resource type - Journals
ISSN - 1617-7061
DOI - 10.1002/pamm.200701092
Subject(s) - protocol (science) , immunotherapy , set (abstract data type) , cancer immunotherapy , feedback control , computer science , order (exchange) , control (management) , state (computer science) , control theory (sociology) , mathematical economics , mathematics , mathematical optimization , cancer , medicine , economics , algorithm , engineering , control engineering , artificial intelligence , finance , alternative medicine , pathology , programming language
We set immunotherapy control as a target control problem under state‐control constraints, taking into account a general tumor dynamics. Then we use a set‐valued approach based on viability theory to build feedback protocol laws by which cancer cells are asymptotically destroyed. An immunotherapy model is examined in order to illustrate our approach. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)