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Computational models for the numerical simulation of voltage operated channels in nano–bio–electronics
Author(s) -
Longaretti Massimo,
Jerome Joseph W.,
Sacco Riccardo,
Chini Bice
Publication year - 2007
Publication title -
pamm
Language(s) - English
Resource type - Journals
ISSN - 1617-7061
DOI - 10.1002/pamm.200700584
Subject(s) - decoupling (probability) , discretization , finite element method , electronics , partial differential equation , ordinary differential equation , ode , computer science , voltage , computational science , electronic engineering , differential equation , mathematics , control engineering , engineering , physics , electrical engineering , mathematical analysis , thermodynamics
In this article, we discuss the use of computational models in the study of voltage operated channels (VOCs) for bio‐electronic applications. Electrochemical and fluid–mechanical ionic transport are described through the coupled use of systems of partial and ordinary differential equations (PDEs and ODEs). Functional iteration techniques for system decoupling and mixed–hybridized finite element discretization methods are proposed and validated in the simulation of realistic problems in Electrophysiology and Biochemistry. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)