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DNA supercoiling modeling of nucleosome and viral spooling
Author(s) -
Maggioni Francesca,
Ricca Renzo L.
Publication year - 2007
Publication title -
pamm
Language(s) - English
Resource type - Journals
ISSN - 1617-7061
DOI - 10.1002/pamm.200700421
Subject(s) - dna supercoil , protein filament , folding (dsp implementation) , nucleosome , dna , computational biology , biophysics , biology , physics , genetics , histone , dna replication , engineering , electrical engineering
New kinematic equations are used to model DNA supercoiling. These equations govern the simultaneous production of multiple folding and coiling of a filament in space by diffeomorphism of a reference curve. Here we show how to use these equations to model regions of highly localized filament coiling, where mechanisms of proteic coding or viral spooling are important. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)