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Why does the positive regulation in bacteriophage λ affect isomerization of the RNAP‐DNA complex?
Author(s) -
Patterson Kate,
Gedeon Tomáš,
Mischaikow Konstantin,
Traldi Eliane
Publication year - 2007
Publication title -
pamm
Language(s) - English
Resource type - Journals
ISSN - 1617-7061
DOI - 10.1002/pamm.200700188
Subject(s) - lysogen , bacteriophage , dna , isomerization , chemistry , affect (linguistics) , biology , biophysics , genetics , biochemistry , escherichia coli , gene , psychology , communication , catalysis
We use a model due to Santillán and Mackey, which is based on the Ackers chemical equilibrium description of the promoter binding by the regulatory factors, to show that the stability of the phage λ lysogen will be severely compromised if CI had a 10‐fold effect on K B and no effect on k . (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)