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A case of oral metastasis of rectal adenocarcinoma with KRAS mutation in patient with synchronous lung adenocarcinoma
Author(s) -
Yamori Masashi,
Kurosawa Manabu
Publication year - 2020
Publication title -
oral science international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.256
H-Index - 13
eISSN - 1881-4204
pISSN - 1348-8643
DOI - 10.1002/osi2.1060
Subject(s) - adenocarcinoma , medicine , kras , colorectal cancer , lung , metastasis , oncology , lung cancer , primary tumor , pathology , cancer
Detecting the origin of the primary cancer that metastasizes in the oral cavity in patients with multiple primary cancers is challenging because of its rarity and complexity. We present an unusual case of an 86‐year‐old women with a maxillary gingival tumor that was histologically proven to be adenocarcinoma; she had been diagnosed with rectal and lung adenocarcinoma. A multidisciplinary approach involving complementary molecular analysis of KRAS gene mutation helped in the diagnosis of metastatic gingival tumor from rectal cancer.