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Unicentric Castleman disease and lymphoepithelial cyst of the parotid: A case report and review of the literature
Author(s) -
Reny Danielle,
Dalal Sharvari,
Jhala Darshana,
Mirza Natasha
Publication year - 2020
Publication title -
oral science international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.256
H-Index - 13
eISSN - 1881-4204
pISSN - 1348-8643
DOI - 10.1002/osi2.1048
Subject(s) - medicine , castleman disease , parotid gland , otorhinolaryngology , lesion , neck mass , parotidectomy , lymphoma , disease , incidence (geometry) , plasmablastic lymphoma , dermatology , pathology , radiology , surgery , physics , optics
Objectives Present the first reported case of unicentric Castleman disease and lymphoepithelial cyst of the parotid in an HIV‐negative adult. Methods Retrospective case presentation. Results Castleman disease is an uncommon disorder of benign hypervascular lymphoid hyperplasia with an estimated incidence rate of 15.9‐19.1 cases per million person‐years (Leukemia & Lymphoma, 56, 2015: 1252). Parotid involvement is extremely rare, with less than 30 cases reported in the literature (Case Reports in Otolaryngology, 2015, 2015: 1). Benign lymphoepithelial cysts (BLECs) are another rare parotid lesion presenting most commonly in HIV‐positive patients. Here we present the case of a 42‐year‐old HIV‐negative male who presented with 3 cm parotid mass. The patient underwent superficial parotidectomy with final pathology demonstrating BLEC with the hyaline‐vascular subtype of Castleman disease. The patient has had no recurrence of symptoms in a 3‐month follow‐up period. Conclusions The practitioner should consider unicentric Castleman disease and BLEC in HIV‐negative patients presenting with a new head and neck mass.