Premium
A difficult‐to‐diagnose case of extranodal NK/T‐cell lymphoma, nasal type, primary to maxillary gingival ulcers that developed after living‐donor liver transplantation
Author(s) -
Kawakami Hiroshi,
Yonenaga Kazumichi,
Suenaga Hideyuki,
Abe Masanobu,
Takato Tsuyoshi,
Hoshi Kazuto
Publication year - 2020
Publication title -
oral science international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.256
H-Index - 13
eISSN - 1881-4204
pISSN - 1348-8643
DOI - 10.1002/osi2.1040
Subject(s) - medicine , t cell lymphoma , lymphoma , malignancy , biopsy , gastroenterology , liver transplantation , transplantation , dermatology , pathology , surgery
Extranodal nasal‐type NK/T‐cell lymphoma (ENKTL) is a hematopoietic malignancy that is rare in the oral cavity. We report a case of a 62‐year‐old woman who developed ENKTL after undergoing living‐donor liver transplantation at the age of 53 years. She had a history of hepatitis C‐related liver cirrhosis. After being diagnosed with necrotizing ulcerative gingivitis, she received antibiotic therapy; however, it was ineffective. Clinical findings suggested a neoplastic disease and necessitated a gingival biopsy. A definitive diagnosis of ENKTL was made based on the immunohistochemical analysis. She achieved a complete clinical response after two courses of SMILE chemotherapy.