Open AccessAptamer‐Based Cancer Cell Analysis and Treatment
Author(s) -
Wu Limei,
Zhang Yutong,
Wang Zhimin,
Zhang Yue,
Zou Jianmei,
Qiu Liping
Publication year - 2022
Publication title -
chemistryopen
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 29
ISSN - 2191-1363
DOI - 10.1002/open.202200141
Subject(s) - aptamer , oligonucleotide , computational biology , nanotechnology , chemistry , dna , combinatorial chemistry , computer science , biology , microbiology and biotechnology , materials science , biochemistry
Aptamers are a class of single‐stranded DNA or RNA oligonucleotides that can exclusively bind to various targets with high affinity and selectivity. Regarded as “chemical antibodies”, aptamers possess several intrinsic advantages, including easy synthesis, convenient modification, high programmability, and good biocompatibility. In recent decades, many studies have demonstrated the superiority of aptamers as molecular tools for various biological applications, particularly in the area of cancer theranostics. In this review, we focus on recent progress in developing aptamer‐based strategies for the precise analysis and treatment of cancer cells.