Open AccessIn Vivo Imaging for the Visualization of Extracellular Vesicle‐Based Tumor Therapy
Author(s) -
Jiang Anqi,
Nie Weidong,
Xie HaiYan
Publication year - 2022
Publication title -
chemistryopen
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 29
ISSN - 2191-1363
DOI - 10.1002/open.202200124
Subject(s) - extracellular vesicles , in vivo , visualization , extracellular vesicle , chemistry , nanotechnology , microbiology and biotechnology , computer science , microvesicles , materials science , biology , biochemistry , artificial intelligence , microrna , gene
Extracellular vesicles (EVs) exhibiting versatile biological functions provide promising prospects as natural therapeutic agents and drug delivery vehicles. For future clinical translation, revealing the fate of EVs in vivo, especially their accumulation at lesion sites, is very important. The continuous development of in vivo imaging technology has made it possible to track the real‐time distribution of EVs. This article reviews the applications of mammal‐, plant‐, and bacteria‐derived EVs in tumor therapy, the labeling methods of EVs for in vivo imaging, the advantages and disadvantages of different imaging techniques, and possible improvements for future work.