Open AccessOne‐Pot Synthesis of Asymmetrically Difunctionalized Oligomaltosides by Cyclodextrin Ring Opening
Author(s) -
Pélingre Matthieu,
Smadhi Meriem,
Bil Abed,
Bonnet Véronique,
Kovensky José
Publication year - 2021
Publication title -
chemistryopen
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 29
ISSN - 2191-1363
DOI - 10.1002/open.202100079
Subject(s) - cyclodextrin , propargyl , hexa , chemistry , azide , ring (chemistry) , combinatorial chemistry , medicinal chemistry , organic chemistry , catalysis
The synthesis of pure difunctionalized hexa‐, hepta‐ and octamaltosides was performed by one‐pot chemical reaction from perbenzoylated cyclodextrin. Oligomaltosides with azide, propargyl or allyl on reducing end and an unprotected hydroxyl group on non‐reducing end were obtained from perbenzoylated α‐, β‐ and γ‐cyclodextrin with 12 to 48 % yields.