Open AccessStructure of Supramers Formed by the Amphiphile Biotin‐CMG‐DOPE
Author(s) -
Zalygin Anton,
Solovyeva Daria,
Vaskan Ivan,
Henry Stephen,
Schaefer Marcel,
Volynsky Pavel,
Tuzikov Alexander,
Korchagina Elena,
Ryzhov Ivan,
Nizovtsev Alexey,
Mochalov Konstantin,
Efremov Roman,
Shtykova Eleonora,
Oleinikov Vladimir,
Bovin Nicolai
Publication year - 2020
Publication title -
chemistryopen
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 29
ISSN - 2191-1363
DOI - 10.1002/open.202000139
Subject(s) - streptavidin , monolayer , biotin , amphiphile , biot number , cover (algebra) , ligand (biochemistry) , avidin , chemistry , polar , polymer science , physics , crystallography , nanotechnology , materials science , receptor , thermodynamics , organic chemistry , engineering , copolymer , quantum mechanics , biochemistry , mechanical engineering , polymer
Abstract Invited for this month's cover is the group of Prof. Nicolai Bovin from the Russian Academy of Sciences. The cover picture shows how a biotin residue initially hidden in a monolayer formed on the surface of a material by biot‐CMG‐DOPE (see top left) is pulled out of the layer by the streptavidin molecule (Str) that has come close to it (see below). This can be considered as a model of certain events (in particular, cis protein‐ligand interactions) occurring on the surface of a living cell when it is necessary to hide the ligand from undesirable interactions, but leave the possibility of its recognition by a high‐affinity protein. The picture is inspired by the legendary Yellow Submarine cartoon. Read the full text of their Full Paper at 10.1002/open.201900276.