Open AccessFront Cover: Rhodol Derivatives as Selective Fluorescent Probes for the Detection of Hg II Ions and the Bioimaging of Hypochlorous Acid (ChemistryOpen 2/2018)
Author(s) -
Li Ling,
Wang Shu,
Lan Hongxia,
Gong Guiyi,
Zhu Yifan,
Tse Yu Chung,
Wong Keith ManChung
Publication year - 2018
Publication title -
chemistryopen
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.644
H-Index - 29
ISSN - 2191-1363
DOI - 10.1002/open.201800009
Subject(s) - hypochlorous acid , fluorescence , chemistry , rhodamine , fluorescein , confocal , mercury (programming language) , hypochlorite , photochemistry , fluorescence lifetime imaging microscopy , front cover , ion , selectivity , fluorescence microscope , hela , cover (algebra) , inorganic chemistry , organic chemistry , biochemistry , in vitro , catalysis , optics , mechanical engineering , physics , computer science , programming language , engineering
The Front Cover shows a novel rhodol‐based fluorescence probe from the structural combination of rhodamine and fluorescein motifs. Through the modification of the functional group on the spiro‐ring, high selectivity and sensitivity towards mercury(II) and hypochlorite ions are achieved, showing a significant color change and fluorescence enhancement. Confocal microscopy images of HeLa cells incubated with the probe show enhanced fluorescence intensity with HClO, thus demonstrating the potential of the probe in further applications for in vivo HOCl detection. More information can be found in the Full Paper by L. Li et al. on page 136 in Issue 2, 2018 (DOI: 10.1002/open.201700154).