Open AccessLabel‐Free Direct Electrical Detection of a Histidine‐Rich Protein with Sub‐Femtomolar Sensitivity using an Organic Field‐Effect Transistor
Author(s) -
Minamiki Tsukuru,
Sasaki Yui,
Tokito Shizuo,
Minami Tsuyoshi
Publication year - 2017
Publication title -
chemistryopen
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 29
ISSN - 2191-1363
DOI - 10.1002/open.201700124
Subject(s) - transistor , organic field effect transistor , biosensor , nanotechnology , field effect transistor , materials science , biomarker , electronic circuit , chip , sensitivity (control systems) , optoelectronics , computer science , chemistry , electronic engineering , electrical engineering , engineering , telecommunications , voltage , biochemistry
The front cover artwork is provided by the group of Dr. Tsuyoshi Minami at the Institute of Industrial Science, the University of Tokyo (Japan). Easy‐to‐use sensing systems for on‐site biomarker testing have been researched numerously, because conventional approaches for biomarker detection (e.g. enzyme linked‐immunosorbent assays, etc.) are too complicated. In that regard, organic filed‐effect transistors (OFETs) are some of the most promising platforms for construction of on‐site testing systems. As OFETs can be easily fabricated on flexible substrates using wet processes, these are not only valuable transducers for chemo‐/biosensors, but also the prospective device for rollable displays and low‐cost radio frequency identification tags. Thus, the components of the sensing system could be integrated into a single chip by using OFET‐based circuits. For more details, see the full text of the Communication at 10.1002/open.201700070.