A Platform for Specific Delivery of Lanthanide–Scandium Mixed‐Metal Cluster Fullerenes into Target Cells | Zendy

Svitova Anna | Zendy; Braun Klaus | Zendy; Popov Alexey A. | Zendy; Dunsch Lothar | Zendy

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A Platform for Specific Delivery of Lanthanide–Scandium Mixed‐Metal Cluster Fullerenes into Target Cells

Author(s) -

Svitova Anna,

Braun Klaus,

Popov Alexey A.,

Dunsch Lothar

Publication year - 2012

Publication title -

chemistryopen

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.644

H-Index - 29

ISSN - 2191-1363

DOI - 10.1002/open.201200023

Subject(s) - scandium , lanthanide , fullerene , cluster (spacecraft) , nanotechnology , metal , materials science , chemistry , inorganic chemistry , computer science , organic chemistry , metallurgy , ion , programming language

A shuttle into cells: A modular c‐myc‐antisense‐Gd@BioShuttle system (see figure), comprising a gadolinium‐ containing nitride cluster fullerene as an imaging component, an address module (nuclear localization sequence) and a transmembrane carrier peptide, is prepared, and its facile intracellular localization is proven by in vitro studies.

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