Open AccessRhodium‐Catalyzed Rearrangement Reaction of Azabicyclo[4.1.0]heptenes bearing Cyclopropyl and Aryl Groups to Arylhexahydroisoquinolines
Author(s) -
Son Sori,
Kim Sun Young,
Chung Young Keun
Publication year - 2012
Publication title -
chemistryopen
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 29
ISSN - 2191-1363
DOI - 10.1002/open.201200022
Subject(s) - aryl , rhodium , chemistry , catalysis , medicinal chemistry , stereochemistry , organic chemistry , alkyl
Let′s rearrange! Rh(PPh 3 ) 2 (CO)Cl/AgBF 4 has been found to be an efficient catalytic system in the rearrangement of azabicyclo[4.1.0]heptenes having an aryl and a cyclopropyl group in the 1‐ and 6‐position, respectively. This has led to the development of an efficient and simple method for the synthesis of arylhexahydroisoquinolines.
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